To make that vision a reality, we are laser focused on one goal: to discover a biological cure. Nearly 200 couples filled out a survey on measures of relationship satisfaction and depressive symptoms, and then participated in an 8-min video-recorded discussion about T1D in their lives. Current therapies would be more effective when used in patients at high risk for developing type 2 diabetes before the metabolic imbalances set in. This study will determine how effective RA and RA-amide are in ameliorating diabetes and related neurodegeneration in a diabetic animal model. The number of adults diagnosed with diabetes in the United States has more than tripled over the past 20 years. The poster hall alone displayed a whopping 2,000+ research posters. Purpose:Patients with type 2 diabetes have inappropriately high blood sugar levels, which is predominately produced by the liver. The researchers plan to determine how a protein called KSRP controls the insulin signaling pathway and identify factors that are regulated by KSRP and involved in this pathway. Specifically, research… Purpose:Insulin plays an important role in maintaining normal blood glucose levels by activating a series of actions referred to as the insulin signaling pathway in insulin target tissues. However, during diabetes there is impaired vasodilation, and thus impaired neurovascular coupling. Current Research in Diabetes & Obesity Journal, Volume 13, pp 47-57; doi:10.19080/crdoj.2020.13.555870 2019. Current Diabetes Reviews publishes full-length/mini reviews, original research articles, drug clinical trial studies and guest edited issues on all the latest advances on diabetes and its related areas dedicated to clinical research e.g. A look at the dangers of hypoglycemia, why it's so hard to describe, and a new diabetes awareness campaign on low blood sugar. To me, that’s the biggest gap… We aren’t successful with the very effective interventions and treatments we have today. For type 1 diabetes, the quest for an artificial pancreas, in other words a self-functioning insulin pump, has been undergoing a number of different trials to test for safety and effectiveness. With research and awareness in mind, here are some new developments in both Type 1 and Type 2 diabetes. Current Research. Currently 1.25 million Americans live with type 1 diabetes (T1D), including 200,000 children. The 2017 Millennium Award – Type 2 was awarded to Dr Seth Masters of The Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne. This study challenges the critical barrier of existing treatment by testing a novel immunotherapy to advance our knowledge and improve human health. Purpose:Neuropathy eventually affects over 60% of patients with type 1 diabetes. This effect may be related to the anti-inflammatory properties of omega-3 PUFA. Current Research into Cures for Type-1 Diabetes News and updates on potential cures for type-1 diabetes, that are in human (or clinical) trials. The researchers hope that this will lead to an increased number of B-cells that function normally so that the blood sugar levels can be kept under control. Researcher:Melissa Brown, Ph.D., RDAssistant ProfessorUniversity of St. JosephWest Hartford, CT. Purpose: Diabetes is one of the most serious diseases affecting public health in the U.S. today. But the, We found that among people with prediabetes and sufficient vitamin D level, vitamin D supplementation at 4,000 units per day did not significantly reduce the risk of diabetes.”, Innovative Simple Intervention to Improve Adherence, New Diabetes Research Presented at #ADA2019, DiRECT (Diabetes Remission Clinical Trial), Pittsburgh Epidemiology of Diabetes Complications (EDC) study, The Emotional Toll of Diabetes Complications, a study on insulin resistance in dark-dwelling cavefish, I Tried It: Tandem’s New Control-IQ Automated Diabetes Technology. Though diabetes has no known cure right now, you should be aware of the recent medical advances and discoveries as researchers work on finding a cure and improving treatments. The number of adults diagnosed with diabetes in the United States has more than tripled over the past 20 years. Purpose:The incidence of diabetes is increasing rapidly, with decreased functional Beta-cell mass critical for disease progression. Much of the talk centered around information from a study published last year that looked at induction at 38 weeks versus 40 weeks and the impact on infant size and neonatal hypoglycemia. Diabetes Australia supports and develops outstanding diabetes research in Australia. This was a lively Pro and Con discussion led by University of Michigan researcher Jennifer Wyckoff. Researcher:Bin Xu, Ph.D.Assistant ProfessorPrincipal InvestigatorBiomanufacturing Research Institute and Technology Enterprise (BRITE)North Carolina Central UniversityDurham, NC. Diabetes Australia supports and develops outstanding diabetes research in Australia. That was one of many pregnancy-related sessions and research posters presented at ADA. While many organizations and clinicians are embracing TIR these days, we have a long way to go in making it an established measure that researchers, industry and regulators accept into their processes. In this project Dr. Liu will investigate whether a combination treatment with hispidulin and sulforaphane is more effective in preventing T2D development by simultaneously improving insulin sensitivity and preserving functional beta-cell mass in T2D mice. Purpose:Islet transplantation is a promising approach to cure type 1 diabetes and some people with type 2 diabetes, but current treatment requires high dose toxic systemic immunotherapy to prevent rejection. It was a fun pilot study of using an “Innovative Simple Intervention to Improve Adherence“ that Gupta noted could be easily scaled to struggling T1D teens and young adults everywhere. Currently, more than 65% of Americans are overweight or obese, 17 million have DM2, and another 16 million are at high risk for developing the disease within the next 10 years. of Neurology, Anatomy and NeurobiologyVice Chair for Research, Dept. The annual cost of diabetes to our health care system is hundreds of billions of dollars. That’s a big problem for our field and for the diabetes community.”. Since the study started in 2007 over 12,000 people have volunteered within the Exeter area and greater than 60,000 nationwide. The 2015 FDA approved Phase II clinical trial, which  is now fully enrolled with 150 participants with long-term type 1 diabetes, will determine the dose and frequency of doses required to reverse type 1 diabetes. In past years, the ADA handed out guides the size of phone books to all attendees that listed details on every poster and its authors. It certainly is, and when that research is in the field of medicine, the impact on humankind can be immense. Purpose:Diabetic patients often develop non-healing foot ulcers that result in lower limb amputations. “The results have important implications for people, particularly youth, who have relatives with the disease, as these individuals may be at high risk and benefit from early screening and treatment.”. Researcher:Li Zhang, MD, Ph.D., Assistant ProfessorBaylor College of MedicineHouston, TX. For millions of children and adults living with diabetes today, a cure would mean: Researcher:Kai Y. XuAssociate Professor of SurgeryUniversity of Maryland School of MedicineBaltimore, MD. Latest Research on Diabetes. Using data from a landmark observational study, the Coronary Artery Risk Development in Young Adults, this study aims to identify possible differences in the predictors of developing pre-diabetes and type 2 diabetes between early and late onset type 2 diabetes groups. Paper published 12/2017Paper published 12/2017, Researcher:James Russell, MD, MBchB, MS, FACP, FRCPProfessor Dept. StartRight This study aims to achieve more accurate early classification of diabetes and identification of which patients will rapidly require insulin treatment. A research study to help improve treatment of type 2 diabetes, by learning how individuals respond to different blood sugar-lowering drugs. Preliminary epidemiological data support an association between chemical exposure and T1D and there is evidence that such exposures can impact Beta-cell function and contribute to the development of autoimmunity. Type 2 diabetes may also lead to kidney failure, vision loss, and/or amputations. For close to 70 years, the American Diabetes Association (ADA) has dedicated its resources to research, educate, legislate, and fight for progress and against discrimination. But the results, published during the ADA conference, were unfortunately rather “meh.”, The researchers note: “We found that among people with prediabetes and sufficient vitamin D level, vitamin D supplementation at 4,000 units per day did not significantly reduce the risk of diabetes.”. The aim of this project is to determine the molecular mechanisms by which intestine derived cocoa epicatechin metabolites improve functional B-cell mass, and to use this to develop treatments for patients with diabetes.. Diabetes affects an estimated 34.2 million people in the United States and is the seventh leading cause of death. Defects in this pathway result in insulin resistance which predisposes an individual to the development of type 2 diabetes. Interventions that increase Beta-cell mass could be used as a treatment for both type 1 and type 2 diabetes. The mechanism(s) underlying this diabetes-associated cognitive decline is poorly understood but may be related to an increase in diabetes-induced inflammation in the brain. The loss or destruction leads to a decreased amount of B-cells that function normally and ultimately, results in a reduced ability to control blood sugar levels. Why Is Emergency Glucose Packaging so Hard to Open? People with type 1 diabetes are at increased risk for celiac disease (CD), particularly in the early course of diabetes, according to findings from a systematic review of the literature. Our website services, content, and products are for informational purposes only. Pretty mind-blowing…. PURPOSE: To review clinical trials that report interventions to delay or prevent the development of type 2 diabetes mellitus (DM2). Although these phenotypes are observed, these compounds have limited intestinal absorbance and are not observed in circulation. Particularly in the case of chronic conditions such as diabetes, groundbreaking research can transform and save lives. However, they also need to determine if NR can prevent neuropathy in type 1 diabetes and if the effect can be sustained. Of course there were many sessions focused on nutrition and food-related topics, including numerous mentions of the ADA’s Nutrition Consensus Report released earlier this year. The effects of vitamin D on people with diabetes were mentioned in no less than nine research posters. Recent studies reveal that newly developed immunotherapy protects kidney function against progression of type-1 diabetes-induced kidney failure in female NOD mice. Please find 3174 such items on this topic. For humans without genetic long-term over-nutrition, excessive intakes of macronutrients (carbohydrates, fat and proteins) for energy, and micronutrients (vitamins and minerals) for metabolic regulation, play a key role in the process. However, its invasive and non-reversible nature has limited its application to small patient subgroups. TriMaster. Researcher:Teresa DiLorenzo, PhD, ProfessorAlbert Einstein College of MedicineNew York, NY. Particularly in the case of chronic conditions such as diabetes, groundbreaking research can transform and save lives. A recent study out of Utah looked at the potential of marine snail venom to improve insulin effectiveness in humans with diabetes. The goal of this research is to identify low-cost, natural compounds to prevent and treat T2D. At the end of the day, we’re reminded that the ADA Scientific Sessions is indeed a conference by and for medical professionals – something we patients need to keep in mind. Cognitive function is decreased and the incidence of stroke is increased by diabetes. “Our researchers were intrigued by the findings suggesting that blood pressure and glycemia are similarly important for cardiovascular risk prediction in this type 1 diabetes patient group,” said lead study author Dr. Jingchuan Guo. Should women with diabetes or prediabetes be induced at 38 weeks, no matter what? Retinopathy is an eye complication of diabetes and can lead to blindness. The current research, the authors note in their study paper, was made possible thanks, in part, to financial support from the research charity Diabetes UK. What diabetes funding is available generally goes to established scientists. Unfortunately, the 5 year survival rate after lower limb amputation is less than 50%, so there is a critical need to develop wound dressings that will improve healing. current research on diabetes nutrition. Currently 1.25 million Americans live with type 1 diabetes (T1D), including 200,000 children. of NutritionThe University of Tennessee, KnoxvilleKnoxville, TN. Advances in stem cell transplantation may replace the need for insulin in type 1 diabetes and may lead to repair of damaged heart tissue following a heart attack. Findings will provide information to increase the precision of diabetes prevention, identification, and care for individuals at risk for and with early onset type 2 diabetes. One potential molecule link between these diseases is a molecule called amylin. Researcher: Paul Hiers, MDPediatric Endocrine FellowUniversity of FloridaGainesville, FL. a large-scale clinical trial that investigated whether vitamin D supplementation helps prevent or delay type 2 diabetes in adults who are at high risk. This journal publishes research articles, review articles, case reports, mini reviews, editorials and short communications, etc. Type 2 diabetes is the most common form of diabetes. The four-day course is organized by the Danish Diabetes Academy and is aimed at doctoral students with a focus on diabetes epidemiology. Current Diabetes Reviews publishes full-length/mini reviews, original research articles, drug clinical trial studies and guest edited issues on all the latest advances on diabetes and its related areas dedicated to clinical research e.g. Current Research in Clinical Diabetes and Obesity is a peer-reviewed open access journal which publishes emerging concepts and disseminates the ongoing research in multidisciplinary fields of Diabetes and Obesity. However, recent work suggests that not all individuals respond the same way. Recently published articles from Diabetes Research and Clinical Practice. Canadian Journal Of Diabetes Diabetes Canada Professional Section members have full access to current … Professor Curtis and his research team want to test a new drug that could slow or stop retinopathy earlier on in its development. View Study. Recent Diabetes Research and Clinical Practice Articles. TTEH.000513. Type 2 diabetes (T2D) The role of cross-talk between MSCs and cells in the wound environment will be examined using in vitro and animal models that mimic many aspects of type 1 diabetes. Purpose:The rise in the incidence of type 1 diabetes (T1D), especially in industrialized countries, can only be explained by a prevailing influence of environmental factors interacting with common genetic variants that predispose to T1D. These studies will be the first to examine how activation of CB2 receptors may influence cellular pathways responsible for brain damage during diabetes. StartRight This study aims to achieve more accurate early classification of diabetes and identification of which patients will rapidly require insulin treatment. In order to decrease the immunogenic of the mAb1E7, here we propose to humanize the mAb1E7 by replacing its non-functional fragments with human amino acid sequences. The current research, the authors note in their study paper, was made possible thanks, in part, to financial support from the research charity Diabetes UK. It is still necessary to obtain funding to track these patients for an additional five years with the ultimate goal of bringing BCG to market as an approved treatment for type 1 diabetes. The Clinical Research in Type 2 Diabetes (T2D) program supports human studies across the lifespan aimed at understanding, preventing and treating T2D. At the Diabetes Research Institute and Foundation, the vision is a world without diabetes. Excessive secretion of this molecule in T2D patients can lead to the formation of toxic aggregates, which can deposit in the pancreas and the brain and cause damages in these tissues. The Diabetes Care and Education Specialist and the Diabetes Self-management Education Engagement: The 2015 National Practice Survey. Whether micronutrients such as Vitamin A (VA) play a role in type 2 diabetes development is still an open question. Medindia provides you with the latest news and research breakthroughs on Diabetes. Together, these studies will determine whether it is possible to restore the brain’s regulation of blood sugar in type 2 diabetes. current research on diabetes mellitus mellitus 10 code. DiabetesMine reviews Tandem Diabetes exciting new Control-IQ system that partially automates insulin delivery. Diabetes Action Research and Education Foundation, 6701 Democracy Boulevard, Suite 300, Bethesda, MD, 20817, United States. This alternative approach seeks to suppress only those T cells that are responsible for destroying the beta cells. We are the UK’s leading charitable funder of diabetes research. Normally, cerebral blood flow will match metabolic demand (neurovascular coupling). Furthermore, obesity is associated with increased lipid accumulation in many tissues. Purpose:Beta cells in the pancreatic islets are responsible for making insulin, which is essential for controlling how sugar is used in the body. The American Diabetes Association funds a productive research portfolio that offers significant progress and hope for improved outcomes for people with type 1 diabetes. Dr. Tessem’s lab hypothesized that cocoa epicatechins may be metabolized by intestinal bacteria to absorbable compounds that can enhance beta cell function. Approximately 40,000 new patients are diagnosed yearly. Diabetes and Diet Current Research. The proposed investigation will test the hypothesis and examine the efficacy of immunotherapy on both type-1 and type-2 diabetes induced kidney failure. Dr. Xu hypothesizes that this immunotherapy may be a universal disease-modifying intervention for both type-1 and type-2 diabetes-induced kidney failure. Posted by uofat1d June 6, 2020 July 31, 2020 Posted in Uncategorized. Honey has been used for centuries as a complementary treatment for wound healing; however, it is sticky and difficult to apply. (2013). pharmacology, pathogenesis, complications, epidemiology, clinical care and therapy.. The translation of this research into practice has led to reduc-tions in chronic complications and mor-tality in people with diabetes (6). Studies have shown that dysfunction of NKA is associated with diabetic kidney failure, indicating that NKA activity is essential to kidney function. Our research's impact. Interestingly, one of the lead UK study authors, Dr. Roy Taylor, says this may indicate a new focus for type 2 diabetes management and messaging that the medical community should embrace: weight loss is a way to better handle the rising T2D epidemic globally. DiabetesMine provides details on how to stay safe from coronavirus when you have diabetes. This is especially true for people with diabetes. The researchers also hope to facilitate the development of T cells that can suppress the remaining disease-causing T cells. Although the precise mechanisms responsible are not clear, the researchers suggest that impaired dilation of cerebral arterioles may contribute. The SEARCH, TODAY, and HEALTHY studies, and NASN's SCOPE intervention, illustrate that collaboration between schools, school nurses, clinicians, students, and families can help treat and prevent diabetes and obesity in youth. Type 2 diabetes (T2D) T. he burden of diabetes is enormous and escalating at an alarming rate (1–3). ... previously known as juvenile diabetes because it's usually diagnosed in children and young adults. View Study . Diabetes Canada is committed to innovation and breakthrough research that will End Diabetes. Thus, much more effective therapeutic methods may be developed to increase insulin sensitivity in individuals with type 2 diabetes. The first one is a collaboration between Stanford University and the University of California at San Francisco (UCSF), based on their shared work in immune system, beta and stem cell research. The annual cost of diabetes to our health care system is hundreds of billions of dollars. This will allow very early access to the technologies, potentially improving care, improving glycemic control, improving safety, and easing burden of disease months before patients would be able to obtain these technologies normally. New Diabetes Research Presented at #ADA2019 Delaying the Onset of Type 1 Diabetes. Previously we successfully generated a mouse-anti-human insulin specific monoclonal antibody, MAb1E7, and confirmed that mAb1E7 suppresses disease associated auto-reactive lymphocytes of T1D patients. A study found that despite all the fear of high blood sugars, higher blood pressure levels are just as dangerous for teens with T1D in developing heart disease. Surgical isolation of the proximal bowel following this surgery is thought to be a critical driver of the observed clinical benefits. This wasn’t the only mention of fish at this year’s conference, btw. In 255 pregnant women followed between 2010 and 2013, and then from 2016 to 2018, A1C levels dropped from 6.8% to 6.5% while the number of women using CGM doubled. Research, including the Diabetes Prevention Program Outcome Study (DPPOS), that evaluates the success of diabetes interventions and strategies. Treatment goals involve tight control of glucose levels to delay the progression of type 2 diabetes and prevent the complications known to significantly decrease the quality of life. Researcher:Kevin W. Huggins, Ph.D.Associate ProfessorAuburn UniversityAuburn, AL. Researcher:EunSeok Cha, Ph.D., MPH, MSN, CDE, RNAssistant ProfessorEmory University Nell Hodson Woodruff  School of NursingAtlanta, GA. Purpose:Individuals with early-onset type 2 diabetes (before age 40) have much greater risks of developing chronic diabetes complications compared to those with late-onset diabetes (after age 40), even if they have had diabetes the same length of time. The study “Early Progression to Diabetes or Regression to Normal Glucose Tolerance” involved a 30-year follow-up to a China-based study, and showed that those who delayed their onset were 30% less likely to develop stroke, heart failure, or myocardial infarction, and 58% less likely to develop complications such as neuropathy, nephropathy, or severe retinopathy during the next 24 years. One of the likely causes is that more women with T1D are using CGMs during pregnancy. Adults up through age 70 need 600 units of vitamin D intake daily and those older than 70 years need 800 units daily. diabetes. One of the quirkiest presentations came from Dr. Olga Gupta of the University of Texas Southwestern Medical Center, who did a study showing that caring for pet fish can help adolescents with higher A1Cs who weren’t previously managing their diabetes as well as they should be. The work we support helps us understand the causes of diabetes, bring about life-changing breakthroughs in care, treatment and prevention and bring us closer to a cure. Lilly and Ypsomed Developing New Automated Insulin Delivery System, Hot New Technology from Medtronic Diabetes, Around the Diabetes Online Community: November 2020, People of Color Speak Out on Diabetes Technology and Care, Everything You Should Know About Coronavirus and Diabetes, The Lowdown on Hypoglycemia (Dangerously Low Blood Sugars). Approximately 40,000 new patients are diagnosed yearly. Researcher:Li Wen, MD, PhDAssociate Professor in MedicineYale University School of MedicineNew Haven, CT. Purpose:Dr. Wen’s lab recently discovered that pancreatic islets from the non-obese diabetic (NOD) mouse, an animal model for human type 1 diabetes, express a high level of biological clock genes. ProfessorPenn State UniversityUniversity Park, PA. Purpose:Dr. Ozbolat previously demonstrated the micro-vascularization of engineered pancreatic islets in fibrin constructs under static conditions, where capillaries sprouted into the constructs facilitating intravascularization in engineered islets as well as capillary network around the islets. Scientists around the world are conducting diabetes research across a phenomenal variety of fields. Researcher:Steven K. Malin, Ph.D., Asst. Despite this, funding has decreased for research to prevent, cure, and better manage the disease. Diabetes News and Research. Learn More. Dr Master’s research focuses on the role of NLRP1 and IL-18 in type 2 diabetes. So naturally, last week’s 79th annual event – held in an unseasonably hot downtown San Francisco – featured updates on loads of new studies from around the country and world, now ready to be presented to medical peers. A research study to help improve treatment of type 2 diabetes, by learning how individuals respond to different blood sugar-lowering drugs. As cases of the novel coronavirus began presenting and comorbidities like diabetes impacted patients at significantly higher rates, we knew that our work to find a cure was more important than ever. At the Forefront of Diabetes Research The U.S. government spends more than $1 billion a year on diabetes research. Type 2 diabetes may also lead to kidney failure, vision loss, and/or amputations. 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